| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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Gene ID | 960 |
Name | CD44 |
Synonymous | CDW44|CSPG8|ECMR-III|HCELL|HUTCH-I|IN|LHR|MC56|MDU2|MDU3|MIC4|Pgp1;CD44 molecule (Indian blood group);CD44;CD44 molecule (Indian blood group) |
Definition | CD44 antigen|GP90 lymphocyte homing/adhesion receptor|Hermes antigen|cell surface glycoprotein CD44|chondroitin sulfate proteoglycan 8|epican|extracellular matrix receptor III|hematopoietic cell E- and L-selectin ligand|heparan sulfate proteoglycan|homing |
Position | 11p13 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
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Transcription Factors [Top] |
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Regulation From TransFac database |
CD44(h) --> CD44-CTF(h) (processing) | IQGAP1(h) + CD44(h) <==> IQGAP1(h):CD44(h) (binding) | CD44(h) + ErbB2(h){p} <==> CD44(h):ErbB2(h){p} (binding) | p85(h) + p110alpha(h) + Hsp50(h) + Hsp90(h) + ezrin(h) + CD44(h) + ErbB2(h){p} <==> p85(h):p110alpha(h):Hsp50(h):Hsp90(h):ezrin(h):CD44(h):ErbB2(h){p} (binding) | p110alpha(h) + Hsp50(h) + ezrin(h) + CD44(h) + ErbB2(h){p} <==> p110alpha(h):Hsp50(h):ezrin(h):CD44(h):ErbB2(h){p} (binding) | Hsp50(h) + ezrin(h) + CD44(h) + ErbB2(h){p} <==> Hsp50(h):ezrin(h):CD44(h):ErbB2(h){p} (binding) | Vav-2(h) + CD44(h) <==> Vav-2(h):CD44(h) (binding) | Vav-2(h) + CD44(h) <==> Vav-2(h):CD44(h) (binding) | Vav-2(h) + Grb-2(h) + CD44(h) + ErbB2(h) <==> Vav-2(h):Grb-2(h):CD44(h):ErbB2(h) (binding) | Grb-2(m.s.) + Vav-2(h) + CD44(h) + ErbB2(h) <==> Grb-2(m.s.):Vav-2(h):CD44(h):ErbB2(h) (binding) | ErbB1(h) + CD44(h) <==> ErbB1(h):CD44(h) (binding) | ErbB1(h) + ErbB2(h) + CD44(h) <==> ErbB1(h):ErbB2(h):CD44(h) (binding) | CD44(h) + nanog(h) <==> CD44(h):nanog(h) (binding) | MDR-1(h) + CD44(h) + ANK2(h) <==> MDR-1(h):CD44(h):ANK2(h) (binding) | CD44(h) + Merlin(h) <==> CD44(h):Merlin(h) (binding) | CD44(h) + OPN(h) <==> CD44(h):OPN(h) (binding) | CD44(h) --> CD44(h) (expression). | CD44(h) --> CD44-isoform2(h) (expression). | CD44(h) --> CD44-isoform1(h) (expression). | CD44(h) --> CD44-isoform3(h) (expression). | CD44(h) --> CD44-isoform4(h) (expression). | CD44(h) --> CD44-isoform5(h) (expression). | CD44(h) --> CD44-isoform6(h) (expression). | CD44(h) --> CD44-isoform7(h) (expression). | CD44(h) --> CD44-isoform8(h) (expression). | CD44(h) --> CD44-isoform9(h) (expression). | CD44(h) --> CD44-isoform10(h) (expression). | CD44(h) --> CD44-isoform11(h) (expression). | CD44(h) --> CD44-isoform12(h) (expression). | CD44(h) --> CD44-isoform13(h) (expression). | CD44(h) --> CD44-isoform14(h) (expression). | CD44(h) --> CD44-isoform15(h) (expression). | CD44(h) --> CD44-isoform16(h) (expression). | CD44(h) --> CD44-isoform17(h) (expression). | CD44(h) --> CD44(h) (expression). | hsa-miR-328 --/ CD44(h) (translational repression). |
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Post Transcriptional Modification [Top] | |||
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Location (AA) |
PTM type |
Literature |
Database |
21 | Pyrrolidone carboxylic acid (Probable). | Swiss-Prot 53.0 | 25 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 57 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 100 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 110 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 120 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 350 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 548 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 599 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 636 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 672 | Phosphoserine; by PKC. | Swiss-Prot 53.0 | 686 | Phosphoserine. | Swiss-Prot 53.0 | 697 | Phosphoserine. | Swiss-Prot 53.0 | 706 | Phosphoserine. | Swiss-Prot 53.0 | 720 | Phosphothreonine. | Swiss-Prot 53.0 | 686 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 697 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 720 | Phosphothreonine | 17081983 | Phospho.ELM 6.0 | 672 | Phosphoserine (PKC alpha) | 12032545 | Phospho.ELM 6.0 | 706 | Phosphoserine | 12032545;17081983 | Phospho.ELM 6.0 |
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Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr11 |
Promoter: 35115493 - 35117493 | Agilent_014791 |
chr11 |
Promoter: 35115493 - 35117493 | GoldenGate_Methylation_Cancer_Panel_I |
chr11 |
Promoter: 35115493 - 35117493 | GoldenGate_Methylation_Cancer_Panel_I |
chr11 |
Promoter: 35115493 - 35117493 | GoldenGate_Methylation_Cancer_Panel_I |
chr11 |
Promoter: 35115493 - 35117493 | GoldenGate_Methylation_Cancer_Panel_I |
chr11 |
Promoter: 35115493 - 35117493 | GoldenGate_Methylation_Cancer_Panel_I |
chr11 |
Promoter: 35115493 - 35117493 | GSE27584 |
chr11 |
Promoter: 35115493 - 35117493 | GSE27584 |
chr11 |
Promoter: 35115493 - 35117493 | GSE27584 |
chr11 |
Promoter: 35115493 - 35117493 | GSE27584 |
chr11 |
Promoter: 35115493 - 35117493 | GSE27584 |
chr11 |
Promoter: 35115493 - 35117493 | Agilent_014791_44K |
chr11 |
Promoter: 35115493 - 35117493 | PMID:15036650 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:15036650 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:15036650 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:15036650 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:15036650 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:12692786 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:12692786 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:12692786 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:12692786 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:12692786 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:15289848 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:15289848 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:15289848 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:15289848 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:15289848 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:16478744 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:16478744 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:16478744 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:16478744 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:16478744 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:10344738 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:10344738 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:10344738 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:10344738 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:10344738 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:17139617 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:17139617 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:17139617 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:17139617 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:17139617 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:11582589 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:11582589 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:11582589 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:11582589 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:11582589 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:12782013 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:12782013 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:12782013 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:12782013 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:12782013 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:12508241 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:12508241 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:12508241 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:12508241 |
chr11 |
Promoter: 35115493 - 35117493 | PMID:12508241 |