Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

9821

Name

RB1CC1

Synonymous

ATG17|CC1|FIP200|PPP1R131;RB1-inducible coiled-coil 1;RB1CC1;RB1-inducible coiled-coil 1

Definition

200 kDa FAK family kinase-interacting protein|FAK family kinase-interacting protein of 200 kDa|RB1-inducible coiled-coil protein 1|phosphatase 1, regulatory subunit 131

Position

8q11

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

rb1cc1(h) + ulk1(m) <==> rb1cc1(h):ulk1(m) (binding)
rb1cc1(h) --> MBP(m.s.){p} (increase of phosphorylation)
rb1cc1(h) + ATP --ulk1(m)--> rb1cc1(h){p} + ADP (phosphorylation)
ulk1(m.s.) + rb1cc1(h) <==> ulk1(m.s.):rb1cc1(h) (binding)
ATG13(h) + rb1cc1(h) <==> ATG13(h):rb1cc1(h) (binding)
rb1cc1(h) + raptor(h) <==> rb1cc1(h):raptor(h) (binding)
rb1cc1(h) + ulk2(m) <==> rb1cc1(h):ulk2(m) (binding)
RB1CC1(h) --> rb1cc1(h) (expression).
ERCC6L(h) + rb1cc1(h) <==> ERCC6L(h):rb1cc1(h) (binding)
CDK11(h) + rb1cc1(h) <==> CDK11(h):rb1cc1(h) (binding)
PREI3(h) + rb1cc1(h) <==> PREI3(h):rb1cc1(h) (binding)
HIP-55(h) + rb1cc1(h) <==> HIP-55(h):rb1cc1(h) (binding)
rb1cc1(h) + ATP --ulk1(h)--> rb1cc1(h){p} + ADP (phosphorylation)
rb1cc1(h) + ATP --ulk2(h)--> rb1cc1(h){p} + ADP (phosphorylation)
ulk1(h) + rb1cc1(h) <==> ulk1(h):rb1cc1(h) (binding)
rb1cc1(h) + ATP --> rb1cc1(h){p} + ADP (phosphorylation)
rb1cc1(h) + ATG13(h) <==> rb1cc1(h):ATG13(h) (binding)
rb1cc1(h) + ulk1(m) <==> rb1cc1(h):ulk1(m) (binding)
RB1CC1(h) --> rb1cc1(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

237Phosphoserine (By similarity).Swiss-Prot 53.0
537Phosphoserine.Swiss-Prot 53.0
666Phosphothreonine (By similarity).Swiss-Prot 53.0
243Phosphoserine17081983Phospho.ELM 6.0
537Phosphoserine17081983Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr8

Promoter: 53789045 - 53791045Agilent_014791

chr8

Promoter: 53789045 - 53791045GSE27584

chr8

Promoter: 53789045 - 53791045Agilent_014791_44K


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