Entrez Gene

Basic Information
Gene ID	9891
Name	NUAK1
Synonymous	ARK5;NUAK family, SNF1-like kinase, 1;NUAK1;NUAK family, SNF1-like kinase, 1
Definition	AMP-activated protein kinase family member 5\|AMPK-related protein kinase 5\|NUAK family SNF1-like kinase 1\|omphalocele kinase 1
Position	12q23.3
Gene Type	protein-coding
Gene Regulation:	Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase [Top]

Regulation From TransFac database
Transcription Factors [Top]
nuak1(h) + ATP --LKB1(m):STRADalpha(h):MO25(h)--> nuak1(h){pT211} + ADP (phosphorylation)
nuak1(h) + ATP --LKB1(m):STRADalpha(h):MO25beta(h)--> nuak1(h){pT211} + ADP (phosphorylation)
nuak1(h) + ATP --LKB1(m):STRADbeta(h):MO25(h)--> nuak1(h){pT211} + ADP (phosphorylation)
nuak1(h) + IGHA-2(h) <==> nuak1(h):IGHA-2(h) (binding)
nuak1(h) + PAP39(h) <==> nuak1(h):PAP39(h) (binding)
nuak1(h) + K1B(h) <==> nuak1(h):K1B(h) (binding)
nuak1(h) + MRP-8(h) <==> nuak1(h):MRP-8(h) (binding)
nuak1(h) + PKA-RI-alpha(h) <==> nuak1(h):PKA-RI-alpha(h) (binding)
nuak1(h) + MRP-14(h) <==> nuak1(h):MRP-14(h) (binding)
NUAK1(h) --> nuak1(h) (expression).
Hsp70-1(h) + nuak1(h) <==> Hsp70-1(h):nuak1(h) (binding)
NUAK1(h) --> nuak1(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Transcriptional Modification [Top]
211	Phosphothreonine.		Swiss-Prot 53.0
215	Phosphoserine (By similarity).		Swiss-Prot 53.0
371	Phosphoserine (By similarity).		Swiss-Prot 53.0
380	Phosphoserine (By similarity).		Swiss-Prot 53.0
600	Phosphoserine (by PKB/AKT1).		Swiss-Prot 53.0
211	Phosphothreonine (LKB1)	14976552	Phospho.ELM 6.0