Bioinformatics and Systems Medicine Laboratory

Browse all tumor suppressor genes by genomic position

Allows users to browse all tumor suppressor genes by their chromosomes. Result shows a list of genes.

                                                                                    

Browse all tumor suppressor genes by data source

Allows users to browse all tumor suppressor genes by data source.

UniProt : 157 human genes annotated with UniProt keyword "Tumor suppressor"    
Tumor Associated Gene database : 170 human tumor suppressor genes were included.    
Generif curation : 632 human genes from 2043 Generif records with tumor suppressor description    
Pubmed Search and curation : 263 human genes from 4864 PubMed abstract curation    

Browse all tumor suppressor genes by data quality

Allows users to browse all tumor suppressor genes by data quality. Result shows a list of genes.

High confidence human gene list: 206 genes found with minimum two data sources and three independent literature supports    
Low confidence human gene list : the other 504 tumor suppressor genes not included in the high confidence gene list    

Browse all tumor suppressor genes by gene type

Allows users to browse all tumor suppressor genes by coding or non-coding genes.

All the human protein coding tumor suppressor genes     
All the human non-coding tumor suppressor genes     

Browse all tumor suppressor genes by popular cancer type

Allows users to browse all tumor suppressor genes by common cancer type.

Breast cancer: 154 TSGs    
Prostate cancer: 87 TSGs    
Rectal cancer: 68 TSGs    
Colon cancer: 57 TSGs    
Ovarian cancer: 54 TSGs    
Small cell lung cancer: 49 TSGs    
Melanoma: 41 TSGs    
Non-small cell lung cancer: 39 TSGs    
Retinoblastoma: 37 TSGs    
Lymphomas: 36 TSGs    
Pancreatic cancer: 33 TSGs    
Leukemias: 30 TSGs    
Cervical cancer: 28 TSGs    
Brain tumor: 27 TSGs    
Acute myeloid leukemia: 27 TSGs    
Neuroblastoma: 25 TSGs    
Nasopharyngeal carcinoma: 18 TSGs    
Thyroid cancer: 16 TSGs    
Bladder cancer: 15 TSGs    
Head and neck cancer: 14 TSGs    
Esophageal cancer: 14 TSGs    
Hodgkin lymphoma: 12 TSGs    
Pheochromocytoma: 10 TSGs    
Non-Hodgkin lymphoma: 10 TSGs    
Chronic lymphocytic leukemia: 10 TSGs    
Endometrial cancer: 9 TSGs    
Oral cancer: 7 TSGs    
Chronic myelogenous leukemia: 7 TSGs    
Pituitary adenoma: 6 TSGs    
Gallbladder cancer: 5 TSGs    
Basal cell carcinoma: 5 TSGs    
Soft tissue sarcoma: 4 TSGs    
Testicular cancer: 3 TSGs    
Liposarcoma: 3 TSGs    
Primary central nervous system lymphoma: 2 TSGs    
Myelodysplastic syndromes: 2 TSGs    
Laryngeal cancer: 2 TSGs    
Kaposi sarcoma: 2 TSGs    
Ependymoma: 2 TSGs    
Burkitt lymphoma: 2 TSGs    
Uterine sarcoma: 1 TSGs    
Stomach cancer: 1 TSGs    
Pharyngeal cancer: 1 TSGs    
Parathyroid cancer: 1 TSGs    
Mycosis fungoides: 1 TSGs    
Merkel cell carcinoma: 1 TSGs    
Extrahepatic bile duct cancer: 1 TSGs    
Cutaneous T-cell lymphoma: 1 TSGs    
Childhood cancers: 1 TSGs    
Anal cancer: 1 TSGs    
AIDS-related lymphoma: 1 TSGs    
AIDS-related cancers: 1 TSGs    
Adrenocortical carcinoma: 1 TSGs    

Browse all tumor suppressor genes by KEGG pathways

Allows users to browse all tumor suppressor genes in KEGG pathway maps. Result shows a KEGG pathway map with a list of genes marked.

Pathways in cancer - Homo sapiens (human)    
HTLV-I infection - Homo sapiens (human)    
Wnt signaling pathway - Homo sapiens (human)    
Cell cycle - Homo sapiens (human)    
Transcriptional misregulation in cancer - Homo sapiens (human)    
p53 signaling pathway - Homo sapiens (human)    
TGF-beta signaling pathway - Homo sapiens (human)    
MAPK signaling pathway - Homo sapiens (human)    
Axon guidance - Homo sapiens (human)    
Herpes simplex infection - Homo sapiens (human)    
All the pathway maps marked with tumor suppressor genes from KEGG could be found here    



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