| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10035131 | HBV | ENSG00000074803.21 | protein_coding | SLC12A1 | No | No | 6557 | Q13621 Q8IUN5 |
| TVIS20002358 | HPV | ENSG00000074803.21 | protein_coding | SLC12A1 | No | No | 6557 | Q13621 Q8IUN5 |
| TVIS20038461 | HPV | ENSG00000074803.21 | protein_coding | SLC12A1 | No | No | 6557 | Q13621 Q8IUN5 |
| TVIS20052244 | HPV | ENSG00000074803.21 | protein_coding | SLC12A1 | No | No | 6557 | Q13621 Q8IUN5 |
| TVIS20025243 | HPV | ENSG00000074803.21 | protein_coding | SLC12A1 | No | No | 6557 | Q13621 Q8IUN5 |
| TVIS44002636 | HTLV-1 | ENSG00000074803.21 | protein_coding | SLC12A1 | No | No | 6557 | Q13621 Q8IUN5 |
| TVIS44029374 | HTLV-1 | ENSG00000074803.21 | protein_coding | SLC12A1 | No | No | 6557 | Q13621 Q8IUN5 |
| TVIS44010135 | HTLV-1 | ENSG00000074803.21 | protein_coding | SLC12A1 | No | No | 6557 | Q13621 Q8IUN5 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SLC12A1 |
|---|---|
| DrugBank ID | DB00214 |
| Drug Name | Torasemide |
| Target ID | BE0000502 |
| UniProt ID | Q13621 |
| Regulation Type | inhibitor |
| PubMed IDs | 11752352; 17460608; 10406837 |
| Citations | Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Vormfelde SV, Sehrt D, Toliat MR, Schirmer M, Meineke I, Tzvetkov M, Nurnberg P, Brockmoller J: Genetic variation in the renal sodium transporters NKCC2, NCC, and ENaC in relation to the effects of loop diuretic drugs. Clin Pharmacol Ther. 2007 Sep;82(3):300-9. Epub 2007 Apr 25.@@Fortuno A, Muniz P, Ravassa S, Rodriguez JA, Fortuno MA, Zalba G, Diez J: Torasemide inhibits angiotensin II-induced vasoconstriction and intracellular calcium increase in the aorta of spontaneously hypertensive rats. Hypertension. 1999 Jul;34(1):138-43. |
| Groups | Approved |
| Direct Classification | Pyridinesulfonamides |
| SMILES | CC(C)NC(=O)NS(=O)(=O)C1=C(NC2=CC=CC(C)=C2)C=CN=C1 |
| Pathways | Torsemide Action Pathway |
| PharmGKB | PA451733 |
| ChEMBL | CHEMBL1148 |
