| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10035131 | HBV | ENSG00000074803.21 | protein_coding | SLC12A1 | No | No | 6557 | Q13621 Q8IUN5 |
| TVIS20002358 | HPV | ENSG00000074803.21 | protein_coding | SLC12A1 | No | No | 6557 | Q13621 Q8IUN5 |
| TVIS20038461 | HPV | ENSG00000074803.21 | protein_coding | SLC12A1 | No | No | 6557 | Q13621 Q8IUN5 |
| TVIS20052244 | HPV | ENSG00000074803.21 | protein_coding | SLC12A1 | No | No | 6557 | Q13621 Q8IUN5 |
| TVIS20025243 | HPV | ENSG00000074803.21 | protein_coding | SLC12A1 | No | No | 6557 | Q13621 Q8IUN5 |
| TVIS44002636 | HTLV-1 | ENSG00000074803.21 | protein_coding | SLC12A1 | No | No | 6557 | Q13621 Q8IUN5 |
| TVIS44029374 | HTLV-1 | ENSG00000074803.21 | protein_coding | SLC12A1 | No | No | 6557 | Q13621 Q8IUN5 |
| TVIS44010135 | HTLV-1 | ENSG00000074803.21 | protein_coding | SLC12A1 | No | No | 6557 | Q13621 Q8IUN5 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SLC12A1 |
|---|---|
| DrugBank ID | DB00310 |
| Drug Name | Chlorthalidone |
| Target ID | BE0000502 |
| UniProt ID | Q13621 |
| Regulation Type | inhibitor |
| PubMed IDs | 17139284; 17016423; 11752352; 19474192 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Gamba G: The thiazide-sensitive Na+-Cl- cotransporter: molecular biology, functional properties, and regulation by WNKs. Am J Physiol Renal Physiol. 2009 Oct;297(4):F838-48. doi: 10.1152/ajprenal.00159.2009. Epub 2009 May 27. |
| Groups | Approved |
| Direct Classification | Isoindolones |
| SMILES | NS(=O)(=O)C1=C(Cl)C=CC(=C1)C1(O)NC(=O)C2=CC=CC=C12 |
| Pathways | Chlorthalidone Action Pathway |
| PharmGKB | PA448970 |
| ChEMBL | CHEMBL1055 |
