| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10035131 | HBV | ENSG00000074803.21 | protein_coding | SLC12A1 | No | No | 6557 | Q13621 Q8IUN5 |
| TVIS20002358 | HPV | ENSG00000074803.21 | protein_coding | SLC12A1 | No | No | 6557 | Q13621 Q8IUN5 |
| TVIS20038461 | HPV | ENSG00000074803.21 | protein_coding | SLC12A1 | No | No | 6557 | Q13621 Q8IUN5 |
| TVIS20052244 | HPV | ENSG00000074803.21 | protein_coding | SLC12A1 | No | No | 6557 | Q13621 Q8IUN5 |
| TVIS20025243 | HPV | ENSG00000074803.21 | protein_coding | SLC12A1 | No | No | 6557 | Q13621 Q8IUN5 |
| TVIS44002636 | HTLV-1 | ENSG00000074803.21 | protein_coding | SLC12A1 | No | No | 6557 | Q13621 Q8IUN5 |
| TVIS44029374 | HTLV-1 | ENSG00000074803.21 | protein_coding | SLC12A1 | No | No | 6557 | Q13621 Q8IUN5 |
| TVIS44010135 | HTLV-1 | ENSG00000074803.21 | protein_coding | SLC12A1 | No | No | 6557 | Q13621 Q8IUN5 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SLC12A1 |
|---|---|
| DrugBank ID | DB00761 |
| Drug Name | Potassium chloride |
| Target ID | BE0000502 |
| UniProt ID | Q13621 |
| Regulation Type | binder |
| PubMed IDs | 17139284; 17016423; 16093448; 16713495; 16807401; 11752352 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Fujiwara TM, Bichet DG: Molecular biology of hereditary diabetes insipidus. J Am Soc Nephrol. 2005 Oct;16(10):2836-46. Epub 2005 Aug 10.@@Bichet DG: Hereditary polyuric disorders: new concepts and differential diagnosis. Semin Nephrol. 2006 May;26(3):224-33.@@Pressler CA, Heinzinger J, Jeck N, Waldegger P, Pechmann U, Reinalter S, Konrad M, Beetz R, Seyberth HW, Waldegger S: Late-onset manifestation of antenatal Bartter syndrome as a result of residual function of the mutated renal Na+-K+-2Cl- co-transporter. J Am Soc Nephrol. 2006 Aug;17(8):2136-42. Epub 2006 Jun 28.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved; Withdrawn |
| Direct Classification | Alkali metal chlorides |
| SMILES | [Cl-].[K+] |
| Pathways | |
| PharmGKB | PA451055 |
| ChEMBL | CHEMBL1200731 |
