Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10036449HBVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS10050122HBVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS30085065HIVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS20007380HPVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS20007381HPVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS20010779HPVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS20035928HPVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS20057329HPVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS20021555HPVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS20056904HPVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TCGA Plot Options
Drug Information
GeneHRH1
DrugBank IDDB00363
Drug NameClozapine
Target IDBE0000442
UniProt IDP35367
Regulation Typeantagonist
PubMed IDs11752352; 17382376; 7520908
CitationsChen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Roegge CS, Perraut C, Hao X, Levin ED: Histamine H1 receptor involvement in prepulse inhibition and memory function: relevance for the antipsychotic actions of clozapine. Pharmacol Biochem Behav. 2007 Apr;86(4):686-92. Epub 2007 Feb 22.@@Leysen JE, Janssen PM, Megens AA, Schotte A: Risperidone: a novel antipsychotic with balanced serotonin-dopamine antagonism, receptor occupancy profile, and pharmacologic activity. J Clin Psychiatry. 1994 May;55 Suppl:5-12.
GroupsApproved
Direct ClassificationDibenzodiazepines
SMILESCN1CCN(CC1)C1=NC2=CC(Cl)=CC=C2NC2=CC=CC=C12
Pathways
PharmGKBPA449061
ChEMBLCHEMBL42