Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10036449HBVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS10050122HBVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS30085065HIVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS20007380HPVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS20007381HPVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS20010779HPVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS20035928HPVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS20057329HPVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS20021555HPVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS20056904HPVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TCGA Plot Options
Drug Information
GeneHRH1
DrugBank IDDB00540
Drug NameNortriptyline
Target IDBE0000442
UniProt IDP35367
Regulation Typeantagonist
PubMed IDs7855217; 6096660; 6106553
CitationsCusack B, Nelson A, Richelson E: Binding of antidepressants to human brain receptors: focus on newer generation compounds. Psychopharmacology (Berl). 1994 May;114(4):559-65.@@Sadava D, Wilmington K: Tricyclic antidepressant drugs affect histamine receptors in human leukocytes. Life Sci. 1984 Dec 17;35(25):2545-8.@@Taylor JE, Richelson E: High affinity binding of tricyclic antidepressants to histamine H1-receptors: fact and artifact. Eur J Pharmacol. 1980 Oct 3;67(1):41-6.
GroupsApproved
Direct ClassificationDibenzocycloheptenes
SMILESCNCCC=C1C2=CC=CC=C2CCC2=CC=CC=C12
Pathways
PharmGKBPA450657
ChEMBLCHEMBL445