Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10036449HBVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS10050122HBVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS30085065HIVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS20007380HPVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS20007381HPVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS20010779HPVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS20035928HPVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS20057329HPVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS20021555HPVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS20056904HPVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TCGA Plot Options
Drug Information
GeneHRH1
DrugBank IDDB00370
Drug NameMirtazapine
Target IDBE0000442
UniProt IDP35367
Regulation Typeantagonist
PubMed IDs23229983; 27593622; 23728612
CitationsVande Griend JP, Anderson SL: Histamine-1 receptor antagonism for treatment of insomnia. J Am Pharm Assoc (2003). 2012;52(6):e210-9. doi: 10.1331/JAPhA.2012.12051.@@Salvi V, Mencacci C, Barone-Adesi F: H1-histamine receptor affinity predicts weight gain with antidepressants. Eur Neuropsychopharmacol. 2016 Oct;26(10):1673-7. doi: 10.1016/j.euroneuro.2016.08.012. Epub 2016 Sep 1.@@Sato H, Ito C, Tashiro M, Hiraoka K, Shibuya K, Funaki Y, Iwata R, Matsuoka H, Yanai K: Histamine H(1) receptor occupancy by the new-generation antidepressants fluvoxamine and mirtazapine: a positron emission tomography study in healthy volunteers. Psychopharmacology (Berl). 2013 Nov;230(2):227-34. doi: 10.1007/s00213-013-3146-1. Epub 2013 Jun 1.
GroupsApproved
Direct ClassificationPiperazinoazepines
SMILESCN1CCN2C(C1)C1=CC=CC=C1CC1=C2N=CC=C1
PathwaysMirtazapine H1-Antihistamine Action
PharmGKBPA450522
ChEMBLCHEMBL654