| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44039445 | HTLV-1 | ENSG00000106546.14 | protein_coding | AHR | No | No | 196 | P35869 |
| TVIS44034826 | HTLV-1 | ENSG00000106546.14 | protein_coding | AHR | No | No | 196 | P35869 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | AHR |
|---|---|
| DrugBank ID | DB06732 |
| Drug Name | beta-Naphthoflavone |
| Target ID | BE0003721 |
| UniProt ID | P35869 |
| Regulation Type | agonist |
| PubMed IDs | 10620335; 1658599; 27286660 |
| Citations | Klinge CM, Kaur K, Swanson HI: The aryl hydrocarbon receptor interacts with estrogen receptor alpha and orphan receptors COUP-TFI and ERRalpha1. Arch Biochem Biophys. 2000 Jan 1;373(1):163-74.@@Gasiewicz TA, Rucci G: Alpha-naphthoflavone acts as an antagonist of 2,3,7, 8-tetrachlorodibenzo-p-dioxin by forming an inactive complex with the Ah receptor. Mol Pharmacol. 1991 Nov;40(5):607-12.@@Wei KL, Chen FY, Lin CY, Gao GL, Kao WY, Yeh CH, Chen CR, Huang HC, Tsai WR, Jong KJ, Li WJ, Su JG: Activation of aryl hydrocarbon receptor reduces carbendazim-induced cell death. Toxicol Appl Pharmacol. 2016 Sep 1;306:86-97. doi: 10.1016/j.taap.2016.06.004. Epub 2016 Jun 7. |
| Groups | Experimental |
| Direct Classification | Flavones |
| SMILES | O=C1C=C(OC2=C1C1=CC=CC=C1C=C2)C1=CC=CC=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL26260 |
