| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44039445 | HTLV-1 | ENSG00000106546.14 | protein_coding | AHR | No | No | 196 | P35869 |
| TVIS44034826 | HTLV-1 | ENSG00000106546.14 | protein_coding | AHR | No | No | 196 | P35869 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | AHR |
|---|---|
| DrugBank ID | DB08995 |
| Drug Name | Diosmin |
| Target ID | BE0003721 |
| UniProt ID | P35869 |
| Regulation Type | agonist |
| PubMed IDs | 14644660; 9661887; 33302042 |
| Citations | Zhang S, Qin C, Safe SH: Flavonoids as aryl hydrocarbon receptor agonists/antagonists: effects of structure and cell context. Environ Health Perspect. 2003 Dec;111(16):1877-82.@@Ciolino HP, Wang TT, Yeh GC: Diosmin and diosmetin are agonists of the aryl hydrocarbon receptor that differentially affect cytochrome P450 1A1 activity. Cancer Res. 1998 Jul 1;58(13):2754-60.@@Lee J, Song KM, Jung CH: Diosmin restores the skin barrier by targeting the aryl hydrocarbon receptor in atopic dermatitis. Phytomedicine. 2021 Jan;81:153418. doi: 10.1016/j.phymed.2020.153418. Epub 2020 Nov 25. |
| Groups | Approved; Investigational |
| Direct Classification | Flavonoid-7-O-glycosides |
| SMILES | COC1=C(O)C=C(C=C1)C1=CC(=O)C2=C(O)C=C(O[C@@H]3O[C@H](CO[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)[C@@H](O)[C@H](O)[C@H]3O)C=C2O1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL231884 |
