Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS44039445HTLV-1ENSG00000106546.14protein_codingAHRNoNo196P35869
TVIS44034826HTLV-1ENSG00000106546.14protein_codingAHRNoNo196P35869
TCGA Plot Options
Drug Information
GeneAHR
DrugBank IDDB00393
Drug NameNimodipine
Target IDBE0003721
UniProt IDP35869
Regulation Typeagonist
PubMed IDs17327465
CitationsHu W, Sorrentino C, Denison MS, Kolaja K, Fielden MR: Induction of cyp1a1 is a nonspecific biomarker of aryl hydrocarbon receptor activation: results of large scale screening of pharmaceuticals and toxicants in vivo and in vitro. Mol Pharmacol. 2007 Jun;71(6):1475-86. Epub 2007 Feb 27.
GroupsApproved; Investigational
Direct ClassificationDihydropyridinecarboxylic acids and derivatives
SMILESCOCCOC(=O)C1=C(C)NC(C)=C(C1C1=CC(=CC=C1)[N+]([O-])=O)C(=O)OC(C)C
PathwaysNimodipine Action Pathway
PharmGKBPA450633
ChEMBLCHEMBL1428