| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20061334 | HPV | ENSG00000196230.14 | protein_coding | TUBB | No | No | 203068 | P07437 Q5ST81 Q5SU16 |
| TVIS44034137 | HTLV-1 | ENSG00000196230.14 | protein_coding | TUBB | No | No | 203068 | P07437 Q5ST81 Q5SU16 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TUBB |
|---|---|
| DrugBank ID | DB11731 |
| Drug Name | Depatuxizumab mafodotin |
| Target ID | BE0000143 |
| UniProt ID | P07437 |
| Regulation Type | nucleotide exchange blocker |
| PubMed IDs | 2211617; 27518442 |
| Citations | Bai RL, Pettit GR, Hamel E: Binding of dolastatin 10 to tubulin at a distinct site for peptide antimitotic agents near the exchangeable nucleotide and vinca alkaloid sites. J Biol Chem. 1990 Oct 5;265(28):17141-9.@@Waight AB, Bargsten K, Doronina S, Steinmetz MO, Sussman D, Prota AE: Structural Basis of Microtubule Destabilization by Potent Auristatin Anti-Mitotics. PLoS One. 2016 Aug 12;11(8):e0160890. doi: 10.1371/journal.pone.0160890. eCollection 2016. |
| Groups | Investigational |
| Direct Classification | |
| SMILES | |
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| ChEMBL |
