No data available for the specified gene.
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | APP |
|---|---|
| DrugBank ID | DB12034 |
| Drug Name | Gantenerumab |
| Target ID | BE0003392 |
| UniProt ID | P05067 |
| Regulation Type | antagonist |
| PubMed IDs | 21955818; 21987394 |
| Citations | Bohrmann B, Baumann K, Benz J, Gerber F, Huber W, Knoflach F, Messer J, Oroszlan K, Rauchenberger R, Richter WF, Rothe C, Urban M, Bardroff M, Winter M, Nordstedt C, Loetscher H: Gantenerumab: a novel human anti-Abeta antibody demonstrates sustained cerebral amyloid-beta binding and elicits cell-mediated removal of human amyloid-beta. J Alzheimers Dis. 2012;28(1):49-69. doi: 10.3233/JAD-2011-110977.@@Ostrowitzki S, Deptula D, Thurfjell L, Barkhof F, Bohrmann B, Brooks DJ, Klunk WE, Ashford E, Yoo K, Xu ZX, Loetscher H, Santarelli L: Mechanism of amyloid removal in patients with Alzheimer disease treated with gantenerumab. Arch Neurol. 2012 Feb;69(2):198-207. doi: 10.1001/archneurol.2011.1538. Epub 2011 Oct 10. |
| Groups | Investigational |
| Direct Classification | Peptides |
| SMILES | |
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