No data available for the specified gene.
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | APP |
|---|---|
| DrugBank ID | DB14533 |
| Drug Name | Zinc chloride |
| Target ID | BE0003392 |
| UniProt ID | P05067 |
| Regulation Type | ligand |
| PubMed IDs | 24855651 |
| Citations | Mayer MC, Kaden D, Schauenburg L, Hancock MA, Voigt P, Roeser D, Barucker C, Than ME, Schaefer M, Multhaup G: Novel zinc-binding site in the E2 domain regulates amyloid precursor-like protein 1 (APLP1) oligomerization. J Biol Chem. 2014 Jul 4;289(27):19019-30. doi: 10.1074/jbc.M114.570382. Epub 2014 May 22. |
| Groups | Approved; Investigational |
| Direct Classification | Transition metal chlorides |
| SMILES | [Cl-].[Cl-].[Zn++] |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL1200679 |
