No data available for the specified gene.
Target Gene Table
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Drug Information
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| Gene | APP |
|---|---|
| DrugBank ID | DB14580 |
| Drug Name | Lecanemab |
| Target ID | BE0003392 |
| UniProt ID | P05067 |
| Regulation Type | binder |
| PubMed IDs | 27048170; 33865446 |
| Citations | Logovinsky V, Satlin A, Lai R, Swanson C, Kaplow J, Osswald G, Basun H, Lannfelt L: Safety and tolerability of BAN2401--a clinical study in Alzheimer's disease with a protofibril selective Abeta antibody. Alzheimers Res Ther. 2016 Apr 6;8(1):14. doi: 10.1186/s13195-016-0181-2.@@Swanson CJ, Zhang Y, Dhadda S, Wang J, Kaplow J, Lai RYK, Lannfelt L, Bradley H, Rabe M, Koyama A, Reyderman L, Berry DA, Berry S, Gordon R, Kramer LD, Cummings JL: A randomized, double-blind, phase 2b proof-of-concept clinical trial in early Alzheimer's disease with lecanemab, an anti-Abeta protofibril antibody. Alzheimers Res Ther. 2021 Apr 17;13(1):80. doi: 10.1186/s13195-021-00813-8. |
| Groups | Approved; Investigational |
| Direct Classification | Peptides |
| SMILES | |
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