No data available for the specified gene.
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | APP |
|---|---|
| DrugBank ID | DB03754 |
| Drug Name | Tromethamine |
| Target ID | BE0003392 |
| UniProt ID | P05067 |
| Regulation Type | inhibitor |
| PubMed IDs | 8380642 |
| Citations | Arispe N, Rojas E, Pollard HB: Alzheimer disease amyloid beta protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum. Proc Natl Acad Sci U S A. 1993 Jan 15;90(2):567-71. doi: 10.1073/pnas.90.2.567. |
| Groups | Approved |
| Direct Classification | 1,2-aminoalcohols |
| SMILES | NC(CO)(CO)CO |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL1200391 |
