Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20030137HPVENSG00000103546.19protein_codingSLC6A2NoNo6530P23975
TCGA Plot Options
Drug Information
GeneSLC6A2
DrugBank IDDB00543
Drug NameAmoxapine
Target IDBE0000486
UniProt IDP23975
Regulation Typeinhibitor
PubMed IDs17139284; 17016423; 9537821
CitationsOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Tatsumi M, Groshan K, Blakely RD, Richelson E: Pharmacological profile of antidepressants and related compounds at human monoamine transporters. Eur J Pharmacol. 1997 Dec 11;340(2-3):249-58.
GroupsApproved
Direct ClassificationDibenzoxazepines
SMILESClC1=CC2=C(OC3=CC=CC=C3N=C2N2CCNCC2)C=C1
Pathways
PharmGKBPA448405
ChEMBLCHEMBL1113