Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20030137HPVENSG00000103546.19protein_codingSLC6A2NoNo6530P23975
TCGA Plot Options
Drug Information
GeneSLC6A2
DrugBank IDDB00726
Drug NameTrimipramine
Target IDBE0000486
UniProt IDP23975
Regulation Typeinhibitor
PubMed IDs9537821; 21484238
CitationsTatsumi M, Groshan K, Blakely RD, Richelson E: Pharmacological profile of antidepressants and related compounds at human monoamine transporters. Eur J Pharmacol. 1997 Dec 11;340(2-3):249-58.@@Haenisch B, Hiemke C, Bonisch H: Inhibitory potencies of trimipramine and its main metabolites at human monoamine and organic cation transporters. Psychopharmacology (Berl). 2011 Sep;217(2):289-95. doi: 10.1007/s00213-011-2281-9. Epub 2011 Apr 12.
GroupsApproved
Direct ClassificationDibenzazepines
SMILESCC(CN(C)C)CN1C2=CC=CC=C2CCC2=CC=CC=C12
Pathways
PharmGKBPA451791
ChEMBLCHEMBL644