| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20005688 | HPV | ENSG00000159640.17 | protein_coding | ACE | No | No | 1636 | P12821 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ACE |
|---|---|
| DrugBank ID | DB00492 |
| Drug Name | Fosinopril |
| Target ID | BE0000221 |
| UniProt ID | P12821 |
| Regulation Type | inhibitor |
| PubMed IDs | 11752352; 2836111; 11030016; 11329095 |
| Citations | Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Ondetti MA: Structural relationships of angiotensin converting-enzyme inhibitors to pharmacologic activity. Circulation. 1988 Jun;77(6 Pt 2):I74-8.@@Piepho RW: Overview of the angiotensin-converting-enzyme inhibitors. Am J Health Syst Pharm. 2000 Oct 1;57 Suppl 1:S3-7.@@Sharma S, Deitchman D, Eni JS, Gelperin K, Ilgenfritz JP, Blumenthal M: The hemodynamic effects of long-term ACE inhibition with fosinopril in patients with heart failure. Fosinopril Hemodynamics Study Group. Am J Ther. 1999 Jul;6(4):181-9. |
| Groups | Approved |
| Direct Classification | |
| SMILES | CCC(=O)O[C@@H](OP(=O)(CCCCC1=CC=CC=C1)CC(=O)N1C[C@@H](C[C@H]1C(O)=O)C1CCCCC1)C(C)C |
| Pathways | Fosinopril Action Pathway; Fosinopril Metabolism Pathway |
| PharmGKB | PA449710 |
| ChEMBL | CHEMBL3039598 |
