VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
---|---|---|---|---|---|---|---|---|
TVIS20005688 | HPV | ENSG00000159640.17 | protein_coding | ACE | No | No | 1636 | P12821 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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Gene | ACE |
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DrugBank ID | DB00616 |
Drug Name | Candoxatril |
Target ID | BE0000221 |
UniProt ID | P12821 |
Regulation Type | inhibitor |
PubMed IDs | 11300648; 16642666 |
Citations | Dumoulin MJ, Adam A, Rouleau JL, Lamontagne D: Comparison of a vasopeptidase inhibitor with neutral endopeptidase and angiotensin-converting enzyme inhibitors on bradykinin metabolism in the rat coronary bed. J Cardiovasc Pharmacol. 2001 Apr;37(4):359-66.@@Kostova E, Jovanoska E, Zafirov D, Jakovski K, Maleska V, Slaninka-Miceska M: Dual inhibition of angiotensin converting enzyme and neutral endopeptidase produces effective blood pressure control in spontaneously hypertensive rats. Bratisl Lek Listy. 2005;106(12):407-11. |
Groups | Experimental |
Direct Classification | Indanes |
SMILES | COCCOC[C@H](CC1(CCCC1)C(=O)N[C@H]1CC[C@H](CC1)C(O)=O)C(=O)OC1=CC2=C(CCC2)C=C1 |
Pathways | |
PharmGKB | PA164764517 |
ChEMBL | CHEMBL35084 |