Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20005688HPVENSG00000159640.17protein_codingACENoNo1636P12821
TCGA Plot Options
Drug Information
GeneACE
DrugBank IDDB00616
Drug NameCandoxatril
Target IDBE0000221
UniProt IDP12821
Regulation Typeinhibitor
PubMed IDs11300648; 16642666
CitationsDumoulin MJ, Adam A, Rouleau JL, Lamontagne D: Comparison of a vasopeptidase inhibitor with neutral endopeptidase and angiotensin-converting enzyme inhibitors on bradykinin metabolism in the rat coronary bed. J Cardiovasc Pharmacol. 2001 Apr;37(4):359-66.@@Kostova E, Jovanoska E, Zafirov D, Jakovski K, Maleska V, Slaninka-Miceska M: Dual inhibition of angiotensin converting enzyme and neutral endopeptidase produces effective blood pressure control in spontaneously hypertensive rats. Bratisl Lek Listy. 2005;106(12):407-11.
GroupsExperimental
Direct ClassificationIndanes
SMILESCOCCOC[C@H](CC1(CCCC1)C(=O)N[C@H]1CC[C@H](CC1)C(O)=O)C(=O)OC1=CC2=C(CCC2)C=C1
Pathways
PharmGKBPA164764517
ChEMBLCHEMBL35084