| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30007896 | HIV | ENSG00000138363.15 | protein_coding | ATIC | Yes | No | 471 | P31939 |
| TVIS30052334 | HIV | ENSG00000138363.15 | protein_coding | ATIC | Yes | No | 471 | P31939 |
| TVIS30052335 | HIV | ENSG00000138363.15 | protein_coding | ATIC | Yes | No | 471 | P31939 |
| TVIS44037937 | HTLV-1 | ENSG00000138363.15 | protein_coding | ATIC | Yes | No | 471 | P31939 |
| TVIS44037738 | HTLV-1 | ENSG00000138363.15 | protein_coding | ATIC | Yes | No | 471 | P31939 |
| TVIS44037936 | HTLV-1 | ENSG00000138363.15 | protein_coding | ATIC | Yes | No | 471 | P31939 |
| TVIS44044411 | HTLV-1 | ENSG00000138363.15 | protein_coding | ATIC | Yes | No | 471 | P31939 |
| TVIS44037935 | HTLV-1 | ENSG00000138363.15 | protein_coding | ATIC | Yes | No | 471 | P31939 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | ATIC |
|---|---|
| DrugBank ID | DB00563 |
| Drug Name | Methotrexate |
| Target ID | BE0001240 |
| UniProt ID | P31939 |
| Regulation Type | inhibitor |
| PubMed IDs | 24284432 |
| Citations | Inoue K, Yuasa H: Molecular basis for pharmacokinetics and pharmacodynamics of methotrexate in rheumatoid arthritis therapy. Drug Metab Pharmacokinet. 2014;29(1):12-9. Epub 2013 Nov 26. |
| Groups | Approved |
| Direct Classification | Glutamic acid and derivatives |
| SMILES | CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O |
| Pathways | Methotrexate Action Pathway |
| PharmGKB | PA450428 |
| ChEMBL | CHEMBL34259 |
