| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10018264 | HBV | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS30007874 | HIV | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS30082824 | HIV | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS30052178 | HIV | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS30052179 | HIV | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS20001238 | HPV | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS20055080 | HPV | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS44003313 | HTLV-1 | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS44029149 | HTLV-1 | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CASP8 |
|---|---|
| DrugBank ID | DB05103 |
| Drug Name | AN-9 |
| Target ID | BE0003460 |
| UniProt ID | Q14790 |
| Regulation Type | regulator |
| PubMed IDs | 16373710 |
| Citations | Entin-Meer M, Rephaeli A, Yang X, Nudelman A, VandenBerg SR, Haas-Kogan DA: Butyric acid prodrugs are histone deacetylase inhibitors that show antineoplastic activity and radiosensitizing capacity in the treatment of malignant gliomas. Mol Cancer Ther. 2005 Dec;4(12):1952-61. doi: 10.1158/1535-7163.MCT-05-0087. |
| Groups | Investigational |
| Direct Classification | Fatty acid esters |
| SMILES | CCCC(=O)OCOC(=O)C(C)(C)C |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL100014 |
