| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10018264 | HBV | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS30007874 | HIV | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS30082824 | HIV | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS30052178 | HIV | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS30052179 | HIV | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS20001238 | HPV | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS20055080 | HPV | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS44003313 | HTLV-1 | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS44029149 | HTLV-1 | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CASP8 |
|---|---|
| DrugBank ID | DB11752 |
| Drug Name | Bryostatin 1 |
| Target ID | BE0003460 |
| UniProt ID | Q14790 |
| Regulation Type | inhibitor |
| PubMed IDs | 29693282 |
| Citations | Khan TK, Nelson TJ: Protein kinase C activator bryostatin-1 modulates proteasome function. J Cell Biochem. 2018 Aug;119(8):6894-6904. doi: 10.1002/jcb.26887. Epub 2018 Apr 25. |
| Groups | Investigational |
| Direct Classification | |
| SMILES | [H][C@]12C[C@H](OC(C)=O)C(C)(C)[C@](O)(C[C@]3([H])CC(C[C@@]([H])(O3)C=CC(C)(C)[C@]3(O)O[C@@]([H])(CC(=C/C(=O)OC)[C@@H]3OC(=O)C=CC=CCCC)C[C@@]([H])(OC(=O)C[C@H](O)C1)[C@@H](C)O)=CC(=O)OC)O2 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL449158 |
