| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10018264 | HBV | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS30007874 | HIV | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS30082824 | HIV | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS30052178 | HIV | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS30052179 | HIV | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS20001238 | HPV | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS20055080 | HPV | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS44003313 | HTLV-1 | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS44029149 | HTLV-1 | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CASP8 |
|---|---|
| DrugBank ID | DB12843 |
| Drug Name | Oleandrin |
| Target ID | BE0003460 |
| UniProt ID | Q14790 |
| Regulation Type | regulator |
| PubMed IDs | 27886059 |
| Citations | Ma Y, Zhu B, Yong L, Song C, Liu X, Yu H, Wang P, Liu Z, Liu X: Regulation of Intrinsic and Extrinsic Apoptotic Pathways in Osteosarcoma Cells Following Oleandrin Treatment. Int J Mol Sci. 2016 Nov 23;17(11). pii: ijms17111950. doi: 10.3390/ijms17111950. |
| Groups | Experimental; Investigational |
| Direct Classification | Cardenolide glycosides and derivatives |
| SMILES | CO[C@H]1C[C@H](O[C@H]2CC[C@@]3(C)[C@H](CC[C@@H]4[C@@H]3CC[C@]3(C)[C@H]([C@H](C[C@]43O)OC(C)=O)C3=CC(=O)OC3)C2)O[C@@H](C)[C@@H]1O |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL1075789 |
