| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS46001058 | BKPyv | ENSG00000102755.13 | protein_coding | FLT1 | Yes | No | 2321 | L7RSL3 P17948 |
| TVIS46001458 | BKPyv | ENSG00000102755.13 | protein_coding | FLT1 | Yes | No | 2321 | L7RSL3 P17948 |
| TVIS10018710 | HBV | ENSG00000102755.13 | protein_coding | FLT1 | Yes | No | 2321 | L7RSL3 P17948 |
| TVIS30010291 | HIV | ENSG00000102755.13 | protein_coding | FLT1 | Yes | No | 2321 | L7RSL3 P17948 |
| TVIS30017984 | HIV | ENSG00000102755.13 | protein_coding | FLT1 | Yes | No | 2321 | L7RSL3 P17948 |
| TVIS30034815 | HIV | ENSG00000102755.13 | protein_coding | FLT1 | Yes | No | 2321 | L7RSL3 P17948 |
| TVIS30034816 | HIV | ENSG00000102755.13 | protein_coding | FLT1 | Yes | No | 2321 | L7RSL3 P17948 |
| TVIS30034817 | HIV | ENSG00000102755.13 | protein_coding | FLT1 | Yes | No | 2321 | L7RSL3 P17948 |
| TVIS30034818 | HIV | ENSG00000102755.13 | protein_coding | FLT1 | Yes | No | 2321 | L7RSL3 P17948 |
| TVIS30034819 | HIV | ENSG00000102755.13 | protein_coding | FLT1 | Yes | No | 2321 | L7RSL3 P17948 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | FLT1 |
|---|---|
| DrugBank ID | DB01268 |
| Drug Name | Sunitinib |
| Target ID | BE0000029 |
| UniProt ID | P17948 |
| Regulation Type | inhibitor |
| PubMed IDs | 14654525; 17367763 |
| Citations | O'Farrell AM, Foran JM, Fiedler W, Serve H, Paquette RL, Cooper MA, Yuen HA, Louie SG, Kim H, Nicholas S, Heinrich MC, Berdel WE, Bello C, Jacobs M, Scigalla P, Manning WC, Kelsey S, Cherrington JM: An innovative phase I clinical study demonstrates inhibition of FLT3 phosphorylation by SU11248 in acute myeloid leukemia patients. Clin Cancer Res. 2003 Nov 15;9(15):5465-76.@@Roskoski R Jr: Sunitinib: a VEGF and PDGF receptor protein kinase and angiogenesis inhibitor. Biochem Biophys Res Commun. 2007 May 4;356(2):323-8. Epub 2007 Mar 7. |
| Groups | Approved; Investigational |
| Direct Classification | Indolines |
| SMILES | CCN(CC)CCNC(=O)C1=C(C)NC(C=C2/C(=O)NC3=C2C=C(F)C=C3)=C1C |
| Pathways | |
| PharmGKB | PA162372840 |
| ChEMBL | CHEMBL535 |
