| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10006800 | HBV | ENSG00000145888.11 | protein_coding | GLRA1 | No | No | 2741 | P23415 Q14C71 |
| TVIS30084720 | HIV | ENSG00000145888.11 | protein_coding | GLRA1 | No | No | 2741 | P23415 Q14C71 |
| TVIS30063823 | HIV | ENSG00000145888.11 | protein_coding | GLRA1 | No | No | 2741 | P23415 Q14C71 |
| TVIS30063824 | HIV | ENSG00000145888.11 | protein_coding | GLRA1 | No | No | 2741 | P23415 Q14C71 |
| TVIS30063825 | HIV | ENSG00000145888.11 | protein_coding | GLRA1 | No | No | 2741 | P23415 Q14C71 |
| TVIS20060150 | HPV | ENSG00000145888.11 | protein_coding | GLRA1 | No | No | 2741 | P23415 Q14C71 |
| TVIS20059200 | HPV | ENSG00000145888.11 | protein_coding | GLRA1 | No | No | 2741 | P23415 Q14C71 |
| TVIS20018080 | HPV | ENSG00000145888.11 | protein_coding | GLRA1 | No | No | 2741 | P23415 Q14C71 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GLRA1 |
|---|---|
| DrugBank ID | DB00228 |
| Drug Name | Enflurane |
| Target ID | BE0000433 |
| UniProt ID | P23415 |
| Regulation Type | potentiator |
| PubMed IDs | 25807016; 10683198; 16973644 |
| Citations | Borghese CM: The molecular pharmacology of volatile anesthetics. Int Anesthesiol Clin. 2015 Spring;53(2):28-39. doi: 10.1097/AIA.0000000000000060.@@Krasowski MD, Harrison NL: The actions of ether, alcohol and alkane general anaesthetics on GABAA and glycine receptors and the effects of TM2 and TM3 mutations. Br J Pharmacol. 2000 Feb;129(4):731-43.@@Grasshoff C, Antkowiak B: Effects of isoflurane and enflurane on GABAA and glycine receptors contribute equally to depressant actions on spinal ventral horn neurones in rats. Br J Anaesth. 2006 Nov;97(5):687-94. doi: 10.1093/bja/ael239. Epub 2006 Sep 13. |
| Groups | Approved; Investigational; Vet_approved |
| Direct Classification | Organofluorides |
| SMILES | FC(F)OC(F)(F)C(F)Cl |
| Pathways | |
| PharmGKB | PA449461 |
| ChEMBL | CHEMBL1257 |
