Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10006800HBVENSG00000145888.11protein_codingGLRA1NoNo2741P23415
Q14C71
TVIS30084720HIVENSG00000145888.11protein_codingGLRA1NoNo2741P23415
Q14C71
TVIS30063823HIVENSG00000145888.11protein_codingGLRA1NoNo2741P23415
Q14C71
TVIS30063824HIVENSG00000145888.11protein_codingGLRA1NoNo2741P23415
Q14C71
TVIS30063825HIVENSG00000145888.11protein_codingGLRA1NoNo2741P23415
Q14C71
TVIS20060150HPVENSG00000145888.11protein_codingGLRA1NoNo2741P23415
Q14C71
TVIS20059200HPVENSG00000145888.11protein_codingGLRA1NoNo2741P23415
Q14C71
TVIS20018080HPVENSG00000145888.11protein_codingGLRA1NoNo2741P23415
Q14C71
TCGA Plot Options
Drug Information
GeneGLRA1
DrugBank IDDB01043
Drug NameMemantine
Target IDBE0009666
UniProt IDP48167
Regulation Typeinhibitor
PubMed IDs20720132; 23421676
CitationsXia P, Chen HS, Zhang D, Lipton SA: Memantine preferentially blocks extrasynaptic over synaptic NMDA receptor currents in hippocampal autapses. J Neurosci. 2010 Aug 18;30(33):11246-50. doi: 10.1523/JNEUROSCI.2488-10.2010.@@Limapichat W, Yu WY, Branigan E, Lester HA, Dougherty DA: Key binding interactions for memantine in the NMDA receptor. ACS Chem Neurosci. 2013 Feb 20;4(2):255-60. doi: 10.1021/cn300180a. Epub 2012 Dec 7.
GroupsApproved; Investigational
Direct ClassificationMonoalkylamines
SMILESCC12CC3CC(C)(C1)CC(N)(C3)C2
Pathways
PharmGKBPA10364
ChEMBLCHEMBL807