| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10006800 | HBV | ENSG00000145888.11 | protein_coding | GLRA1 | No | No | 2741 | P23415 Q14C71 |
| TVIS30084720 | HIV | ENSG00000145888.11 | protein_coding | GLRA1 | No | No | 2741 | P23415 Q14C71 |
| TVIS30063823 | HIV | ENSG00000145888.11 | protein_coding | GLRA1 | No | No | 2741 | P23415 Q14C71 |
| TVIS30063824 | HIV | ENSG00000145888.11 | protein_coding | GLRA1 | No | No | 2741 | P23415 Q14C71 |
| TVIS30063825 | HIV | ENSG00000145888.11 | protein_coding | GLRA1 | No | No | 2741 | P23415 Q14C71 |
| TVIS20060150 | HPV | ENSG00000145888.11 | protein_coding | GLRA1 | No | No | 2741 | P23415 Q14C71 |
| TVIS20059200 | HPV | ENSG00000145888.11 | protein_coding | GLRA1 | No | No | 2741 | P23415 Q14C71 |
| TVIS20018080 | HPV | ENSG00000145888.11 | protein_coding | GLRA1 | No | No | 2741 | P23415 Q14C71 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | GLRA1 |
|---|---|
| DrugBank ID | DB00898 |
| Drug Name | Ethanol |
| Target ID | BE0000433 |
| UniProt ID | P23415 |
| Regulation Type | agonist |
| PubMed IDs | 17139284; 17016423; 21044637; 20713066; 9452448 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Fuentealba J, Munoz B, Yevenes G, Moraga-Cid G, Perez C, Guzman L, Rigo JM, Aguayo LG: Potentiation and inhibition of glycine receptors by tutin. Neuropharmacology. 2011 Feb-Mar;60(2-3):453-9. doi: 10.1016/j.neuropharm.2010.10.023. Epub 2010 Oct 31.@@Baenziger JE, Corringer PJ: 3D structure and allosteric modulation of the transmembrane domain of pentameric ligand-gated ion channels. Neuropharmacology. 2011 Jan;60(1):116-25. doi: 10.1016/j.neuropharm.2010.08.007. Epub 2010 Aug 14.@@Ye Q, Koltchine VV, Mihic SJ, Mascia MP, Wick MJ, Finn SE, Harrison NL, Harris RA: Enhancement of glycine receptor function by ethanol is inversely correlated with molecular volume at position alpha267. J Biol Chem. 1998 Feb 6;273(6):3314-9. |
| Groups | Approved |
| Direct Classification | Primary alcohols |
| SMILES | CCO |
| Pathways | Disulfiram Action Pathway; Ethanol Degradation |
| PharmGKB | PA448073 |
| ChEMBL | CHEMBL545 |
