| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10006800 | HBV | ENSG00000145888.11 | protein_coding | GLRA1 | No | No | 2741 | P23415 Q14C71 |
| TVIS30084720 | HIV | ENSG00000145888.11 | protein_coding | GLRA1 | No | No | 2741 | P23415 Q14C71 |
| TVIS30063823 | HIV | ENSG00000145888.11 | protein_coding | GLRA1 | No | No | 2741 | P23415 Q14C71 |
| TVIS30063824 | HIV | ENSG00000145888.11 | protein_coding | GLRA1 | No | No | 2741 | P23415 Q14C71 |
| TVIS30063825 | HIV | ENSG00000145888.11 | protein_coding | GLRA1 | No | No | 2741 | P23415 Q14C71 |
| TVIS20060150 | HPV | ENSG00000145888.11 | protein_coding | GLRA1 | No | No | 2741 | P23415 Q14C71 |
| TVIS20059200 | HPV | ENSG00000145888.11 | protein_coding | GLRA1 | No | No | 2741 | P23415 Q14C71 |
| TVIS20018080 | HPV | ENSG00000145888.11 | protein_coding | GLRA1 | No | No | 2741 | P23415 Q14C71 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GLRA1 |
|---|---|
| DrugBank ID | DB00431 |
| Drug Name | Lindane |
| Target ID | BE0000433 |
| UniProt ID | P23415 |
| Regulation Type | antagonist |
| PubMed IDs | 12614680; 20600211 |
| Citations | Vale C, Fonfria E, Bujons J, Messeguer A, Rodriguez-Farre E, Sunol C: The organochlorine pesticides gamma-hexachlorocyclohexane (lindane), alpha-endosulfan and dieldrin differentially interact with GABA(A) and glycine-gated chloride channels in primary cultures of cerebellar granule cells. Neuroscience. 2003;117(2):397-403.@@Heusinkveld HJ, Thomas GO, Lamot I, van den Berg M, Kroese AB, Westerink RH: Dual actions of lindane (gamma-hexachlorocyclohexane) on calcium homeostasis and exocytosis in rat PC12 cells. Toxicol Appl Pharmacol. 2010 Oct 1;248(1):12-9. doi: 10.1016/j.taap.2010.06.013. Epub 2010 Jun 21. |
| Groups | Approved; Withdrawn |
| Direct Classification | Cyclohexyl halides |
| SMILES | Cl[C@H]1[C@H](Cl)[C@@H](Cl)[C@@H](Cl)[C@H](Cl)[C@H]1Cl |
| Pathways | |
| PharmGKB | PA164754914 |
| ChEMBL | CHEMBL15891 |
