| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44012666 | HTLV-1 | ENSG00000123360.12 | protein_coding | PDE1B | No | No | 5153 | B4DK72 Q01064 |
| TVIS44020579 | HTLV-1 | ENSG00000123360.12 | protein_coding | PDE1B | No | No | 5153 | B4DK72 Q01064 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PDE1B |
|---|---|
| DrugBank ID | DB00622 |
| Drug Name | Nicardipine |
| Target ID | BE0003323 |
| UniProt ID | Q01064 |
| Regulation Type | inhibitor |
| PubMed IDs | 9231746 |
| Citations | Sharma RK, Wang JH, Wu Z: Mechanisms of inhibition of calmodulin-stimulated cyclic nucleotide phosphodiesterase by dihydropyridine calcium antagonists. J Neurochem. 1997 Aug;69(2):845-50. |
| Groups | Approved; Investigational |
| Direct Classification | Dihydropyridinecarboxylic acids and derivatives |
| SMILES | COC(=O)C1=C(C)NC(C)=C(C1C1=CC(=CC=C1)[N+]([O-])=O)C(=O)OCCN(C)CC1=CC=CC=C1 |
| Pathways | |
| PharmGKB | PA450620 |
| ChEMBL | CHEMBL1484 |
