| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44012666 | HTLV-1 | ENSG00000123360.12 | protein_coding | PDE1B | No | No | 5153 | B4DK72 Q01064 |
| TVIS44020579 | HTLV-1 | ENSG00000123360.12 | protein_coding | PDE1B | No | No | 5153 | B4DK72 Q01064 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PDE1B |
|---|---|
| DrugBank ID | DB01113 |
| Drug Name | Papaverine |
| Target ID | BE0009789 |
| UniProt ID | O76074 |
| Regulation Type | inhibitor |
| PubMed IDs | 12215855 |
| Citations | Uckert S, Stief CG, Lietz B, Burmester M, Jonas U, Machtens SA: Possible role of bioactive peptides in the regulation of human detrusor smooth muscle - functional effects in vitro and immunohistochemical presence. World J Urol. 2002 Sep;20(4):244-9. doi: 10.1007/s00345-002-0287-y. Epub 2002 Jul 23. |
| Groups | Approved; Investigational |
| Direct Classification | Benzylisoquinolines |
| SMILES | COC1=C(OC)C=C(CC2=NC=CC3=CC(OC)=C(OC)C=C23)C=C1 |
| Pathways | |
| PharmGKB | PA164745550 |
| ChEMBL | CHEMBL19224 |