| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44012666 | HTLV-1 | ENSG00000123360.12 | protein_coding | PDE1B | No | No | 5153 | B4DK72 Q01064 |
| TVIS44020579 | HTLV-1 | ENSG00000123360.12 | protein_coding | PDE1B | No | No | 5153 | B4DK72 Q01064 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PDE1B |
|---|---|
| DrugBank ID | DB01023 |
| Drug Name | Felodipine |
| Target ID | BE0003323 |
| UniProt ID | Q01064 |
| Regulation Type | inhibitor |
| PubMed IDs | 2933041; 9231746 |
| Citations | Lamers JM, Cysouw KJ, Verdouw PD: Slow calcium channel blockers and calmodulin. Effect of felodipine, nifedipine, prenylamine and bepridil on cardiac sarcolemmal calcium pumping ATPase. Biochem Pharmacol. 1985 Nov 1;34(21):3837-43.@@Sharma RK, Wang JH, Wu Z: Mechanisms of inhibition of calmodulin-stimulated cyclic nucleotide phosphodiesterase by dihydropyridine calcium antagonists. J Neurochem. 1997 Aug;69(2):845-50. |
| Groups | Approved; Investigational |
| Direct Classification | Dihydropyridinecarboxylic acids and derivatives |
| SMILES | CCOC(=O)C1=C(C)NC(C)=C(C1C1=C(Cl)C(Cl)=CC=C1)C(=O)OC |
| Pathways | Felodipine Metabolism Pathway; Felodipine Action Pathway |
| PharmGKB | PA449591 |
| ChEMBL | CHEMBL1480 |
