| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30008124 | HIV | ENSG00000128271.22 | protein_coding | ADORA2A | No | No | 135 | P29274 X5DNB4 |
| TVIS44031350 | HTLV-1 | ENSG00000128271.22 | protein_coding | ADORA2A | No | No | 135 | P29274 X5DNB4 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ADORA2A |
|---|---|
| DrugBank ID | DB00358 |
| Drug Name | Mefloquine |
| Target ID | BE0000924 |
| UniProt ID | P29274 |
| Regulation Type | antagonist |
| PubMed IDs | 18406614 |
| Citations | Gillespie RJ, Adams DR, Bebbington D, Benwell K, Cliffe IA, Dawson CE, Dourish CT, Fletcher A, Gaur S, Giles PR, Jordan AM, Knight AR, Knutsen LJ, Lawrence A, Lerpiniere J, Misra A, Porter RH, Pratt RM, Shepherd R, Upton R, Ward SE, Weiss SM, Williamson DS: Antagonists of the human adenosine A2A receptor. Part 1: Discovery and synthesis of thieno[3,2-d]pyrimidine-4-methanone derivatives. Bioorg Med Chem Lett. 2008 May 1;18(9):2916-9. doi: 10.1016/j.bmcl.2008.03.075. Epub 2008 Mar 30. |
| Groups | Approved; Investigational |
| Direct Classification | 4-quinolinemethanols |
| SMILES | OC(C1CCCCN1)C1=CC(=NC2=C1C=CC=C2C(F)(F)F)C(F)(F)F |
| Pathways | |
| PharmGKB | PA450348 |
| ChEMBL | CHEMBL416956 |
