Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30008124HIVENSG00000128271.22protein_codingADORA2ANoNo135P29274
X5DNB4
TVIS44031350HTLV-1ENSG00000128271.22protein_codingADORA2ANoNo135P29274
X5DNB4
TCGA Plot Options
Drug Information
GeneADORA2A
DrugBank IDDB00683
Drug NameMidazolam
Target IDBE0000924
UniProt IDP29274
Regulation Typepotentiator
PubMed IDs10691246
CitationsSeubert CN, Morey TE, Martynyuk AE, Cucchiara RF, Dennis DM: Midazolam selectively potentiates the A(2A) - but not A1- receptor--mediated effects of adenosine: role of nucleoside transport inhibition and clinical implications. Anesthesiology. 2000 Feb;92(2):567-77. doi: 10.1097/00000542-200002000-00041.
GroupsApproved; Illicit
Direct ClassificationImidazo[1,5-a][1,4]benzodiazepines
SMILESCC1=NC=C2CN=C(C3=CC=CC=C3F)C3=C(C=CC(Cl)=C3)N12
Pathways
PharmGKBPA450496
ChEMBLCHEMBL655