Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30008124HIVENSG00000128271.22protein_codingADORA2ANoNo135P29274
X5DNB4
TVIS44031350HTLV-1ENSG00000128271.22protein_codingADORA2ANoNo135P29274
X5DNB4
TCGA Plot Options
Drug Information
GeneADORA2A
DrugBank IDDB00555
Drug NameLamotrigine
Target IDBE0000924
UniProt IDP29274
Regulation Typeinhibitor
PubMed IDs22306746
CitationsAbelaira HM, Reus GZ, Ribeiro KF, Zappellini G, Cipriano AL, Scaini G, Streck EL, Quevedo J: Lamotrigine treatment reverses depressive-like behavior and alters BDNF levels in the brains of maternally deprived adult rats. Pharmacol Biochem Behav. 2012 May;101(3):348-53. doi: 10.1016/j.pbb.2012.01.019. Epub 2012 Jan 27.
GroupsApproved; Investigational
Direct ClassificationDichlorobenzenes
SMILESNC1=NC(N)=C(N=N1)C1=C(Cl)C(Cl)=CC=C1
Pathways
PharmGKBPA450164
ChEMBLCHEMBL741