Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30081548HIVENSG00000176884.17protein_codingGRIN1NoNo2902Q05586
Q5VSF9
TVIS30072672HIVENSG00000176884.17protein_codingGRIN1NoNo2902Q05586
Q5VSF9
TCGA Plot Options
Drug Information
GeneGRIN1
DrugBank IDDB01043
Drug NameMemantine
Target IDBE0000365
UniProt IDQ05586
Regulation Typebinder
PubMed IDs19687120
CitationsKotermanski SE, Wood JT, Johnson JW: Memantine binding to a superficial site on NMDA receptors contributes to partial trapping. J Physiol. 2009 Oct 1;587(Pt 19):4589-604. doi: 10.1113/jphysiol.2009.176297. Epub 2009 Aug 17.
GroupsApproved; Investigational
Direct ClassificationMonoalkylamines
SMILESCC12CC3CC(C)(C1)CC(N)(C3)C2
Pathways
PharmGKBPA10364
ChEMBLCHEMBL807