| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30081548 | HIV | ENSG00000176884.17 | protein_coding | GRIN1 | No | No | 2902 | Q05586 Q5VSF9 |
| TVIS30072672 | HIV | ENSG00000176884.17 | protein_coding | GRIN1 | No | No | 2902 | Q05586 Q5VSF9 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GRIN1 |
|---|---|
| DrugBank ID | DB01173 |
| Drug Name | Orphenadrine |
| Target ID | BE0000365 |
| UniProt ID | Q05586 |
| Regulation Type | antagonist |
| PubMed IDs | 17139284; 17016423; 8788072 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Kornhuber J, Parsons CG, Hartmann S, Retz W, Kamolz S, Thome J, Riederer P: Orphenadrine is an uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist: binding and patch clamp studies. J Neural Transm Gen Sect. 1995;102(3):237-46. |
| Groups | Approved |
| Direct Classification | Diphenylmethanes |
| SMILES | CN(C)CCOC(C1=CC=CC=C1)C1=CC=CC=C1C |
| Pathways | Orphenadrine H1-Antihistamine Action |
| PharmGKB | PA450715 |
| ChEMBL | CHEMBL900 |
