Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30081548HIVENSG00000176884.17protein_codingGRIN1NoNo2902Q05586
Q5VSF9
TVIS30072672HIVENSG00000176884.17protein_codingGRIN1NoNo2902Q05586
Q5VSF9
TCGA Plot Options
Drug Information
GeneGRIN1
DrugBank IDDB03929
Drug NameD-Serine
Target IDBE0000365
UniProt IDQ05586
Regulation Type
PubMed IDs17139284; 17016423; 10592235
CitationsOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
GroupsApproved; Experimental
Direct ClassificationSerine and derivatives
SMILESN[C@H](CO)C(O)=O
PathwaysDemeclocycline Action Pathway; Josamycin Action Pathway; Kanamycin Action Pathway; Lincomycin Action Pathway; Gentamicin Action Pathway; Azithromycin Action Pathway; Methacycline Action Pathway; Non-Ketotic Hyperglycinemia; Clarithromycin Action Pathway; Minocycline Action Pathway; Paromomycin Action Pathway; Lymecycline Action Pathway; Glycine and Serine Metabolism; Troleandomycin Action Pathway; Amikacin Action Pathway; Dimethylglycine Dehydrogenase Deficiency; Oxytetracycline Action Pathway; Tetracycline Action Pathway; Doxycycline Action Pathway; Spectinomycin Action Pathway; Erythromycin Action Pathway; Dihydropyrimidine Dehydrogenase Deficiency (DHPD); Telithromycin Action Pathway; Neomycin Action Pathway; Roxithromycin Action Pathway; Tigecycline Action Pathway; Sarcosinemia; Arbekacin Action Pathway; Chloramphenicol Action Pathway; Clindamycin Action Pathway
PharmGKB
ChEMBLCHEMBL285123