| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30081548 | HIV | ENSG00000176884.17 | protein_coding | GRIN1 | No | No | 2902 | Q05586 Q5VSF9 |
| TVIS30072672 | HIV | ENSG00000176884.17 | protein_coding | GRIN1 | No | No | 2902 | Q05586 Q5VSF9 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GRIN1 |
|---|---|
| DrugBank ID | DB06151 |
| Drug Name | Acetylcysteine |
| Target ID | BE0000365 |
| UniProt ID | Q05586 |
| Regulation Type | activator |
| PubMed IDs | 12183209; 27179791 |
| Citations | Lipton SA, Choi YB, Takahashi H, Zhang D, Li W, Godzik A, Bankston LA: Cysteine regulation of protein function--as exemplified by NMDA-receptor modulation. Trends Neurosci. 2002 Sep;25(9):474-80.@@Wright DJ, Gray LJ, Finkelstein DI, Crouch PJ, Pow D, Pang TY, Li S, Smith ZM, Francis PS, Renoir T, Hannan AJ: N-acetylcysteine modulates glutamatergic dysfunction and depressive behavior in Huntington's disease. Hum Mol Genet. 2016 Jul 15;25(14):2923-2933. doi: 10.1093/hmg/ddw144. Epub 2016 May 14. |
| Groups | Approved; Investigational |
| Direct Classification | N-acyl-L-alpha-amino acids |
| SMILES | CC(=O)N[C@@H](CS)C(O)=O |
| Pathways | |
| PharmGKB | PA448033 |
| ChEMBL | CHEMBL600 |
