| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30027118 | HIV | ENSG00000196139.14 | protein_coding | AKR1C3 | No | No | 8644 | A0A0A0MSS8 P42330 |
| TVIS20007304 | HPV | ENSG00000196139.14 | protein_coding | AKR1C3 | No | No | 8644 | A0A0A0MSS8 P42330 |
| TVIS20007305 | HPV | ENSG00000196139.14 | protein_coding | AKR1C3 | No | No | 8644 | A0A0A0MSS8 P42330 |
| TVIS20007306 | HPV | ENSG00000196139.14 | protein_coding | AKR1C3 | No | No | 8644 | A0A0A0MSS8 P42330 |
| TVIS20013263 | HPV | ENSG00000196139.14 | protein_coding | AKR1C3 | No | No | 8644 | A0A0A0MSS8 P42330 |
| TVIS20021893 | HPV | ENSG00000196139.14 | protein_coding | AKR1C3 | No | No | 8644 | A0A0A0MSS8 P42330 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | AKR1C3 |
|---|---|
| DrugBank ID | DB01698 |
| Drug Name | Rutin |
| Target ID | BE0000592 |
| UniProt ID | P42330 |
| Regulation Type | |
| PubMed IDs | 19007764; 18949601 |
| Citations | Skarydova L, Zivna L, Xiong G, Maser E, Wsol V: AKR1C3 as a potential target for the inhibitory effect of dietary flavonoids. Chem Biol Interact. 2009 Mar 16;178(1-3):138-44. doi: 10.1016/j.cbi.2008.10.015. Epub 2008 Oct 19.@@Barski OA, Tipparaju SM, Bhatnagar A: The aldo-keto reductase superfamily and its role in drug metabolism and detoxification. Drug Metab Rev. 2008;40(4):553-624. doi: 10.1080/03602530802431439. |
| Groups | Approved; Experimental; Investigational |
| Direct Classification | Flavonoid-3-O-glycosides |
| SMILES | C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](OC3=C(OC4=CC(O)=CC(O)=C4C3=O)C3=CC(O)=C(O)C=C3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O |
| Pathways | |
| PharmGKB | PA451291 |
| ChEMBL | CHEMBL226335 |
