| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30027118 | HIV | ENSG00000196139.14 | protein_coding | AKR1C3 | No | No | 8644 | A0A0A0MSS8 P42330 |
| TVIS20007304 | HPV | ENSG00000196139.14 | protein_coding | AKR1C3 | No | No | 8644 | A0A0A0MSS8 P42330 |
| TVIS20007305 | HPV | ENSG00000196139.14 | protein_coding | AKR1C3 | No | No | 8644 | A0A0A0MSS8 P42330 |
| TVIS20007306 | HPV | ENSG00000196139.14 | protein_coding | AKR1C3 | No | No | 8644 | A0A0A0MSS8 P42330 |
| TVIS20013263 | HPV | ENSG00000196139.14 | protein_coding | AKR1C3 | No | No | 8644 | A0A0A0MSS8 P42330 |
| TVIS20021893 | HPV | ENSG00000196139.14 | protein_coding | AKR1C3 | No | No | 8644 | A0A0A0MSS8 P42330 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | AKR1C3 |
|---|---|
| DrugBank ID | DB02266 |
| Drug Name | Flufenamic acid |
| Target ID | BE0000592 |
| UniProt ID | P42330 |
| Regulation Type | |
| PubMed IDs | 17016423; 14996743; 17139284; 10592235 |
| Citations | Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Lovering AL, Ride JP, Bunce CM, Desmond JC, Cummings SM, White SA: Crystal structures of prostaglandin D(2) 11-ketoreductase (AKR1C3) in complex with the nonsteroidal anti-inflammatory drugs flufenamic acid and indomethacin. Cancer Res. 2004 Mar 1;64(5):1802-10.@@Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
| Groups | Approved |
| Direct Classification | Aminobenzoic acids |
| SMILES | OC(=O)C1=CC=CC=C1NC1=CC(=CC=C1)C(F)(F)F |
| Pathways | |
| PharmGKB | PA166049190 |
| ChEMBL | CHEMBL23588 |
