| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30027118 | HIV | ENSG00000196139.14 | protein_coding | AKR1C3 | No | No | 8644 | A0A0A0MSS8 P42330 |
| TVIS20007304 | HPV | ENSG00000196139.14 | protein_coding | AKR1C3 | No | No | 8644 | A0A0A0MSS8 P42330 |
| TVIS20007305 | HPV | ENSG00000196139.14 | protein_coding | AKR1C3 | No | No | 8644 | A0A0A0MSS8 P42330 |
| TVIS20007306 | HPV | ENSG00000196139.14 | protein_coding | AKR1C3 | No | No | 8644 | A0A0A0MSS8 P42330 |
| TVIS20013263 | HPV | ENSG00000196139.14 | protein_coding | AKR1C3 | No | No | 8644 | A0A0A0MSS8 P42330 |
| TVIS20021893 | HPV | ENSG00000196139.14 | protein_coding | AKR1C3 | No | No | 8644 | A0A0A0MSS8 P42330 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | AKR1C3 |
|---|---|
| DrugBank ID | DB09074 |
| Drug Name | Olaparib |
| Target ID | BE0000592 |
| UniProt ID | P42330 |
| Regulation Type | inhibitor |
| PubMed IDs | 33114555 |
| Citations | Tavares TS, Hofman J, Lekesova A, Zelazkova J, Wsol V: Olaparib Synergizes the Anticancer Activity of Daunorubicin via Interaction with AKR1C3. Cancers (Basel). 2020 Oct 26;12(11). pii: cancers12113127. doi: 10.3390/cancers12113127. |
| Groups | Approved |
| Direct Classification | Phthalazinones |
| SMILES | FC1=CC=C(CC2=NNC(=O)C3=CC=CC=C23)C=C1C(=O)N1CCN(CC1)C(=O)C1CC1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL521686 |
