| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20008608 | HPV | ENSG00000167434.10 | protein_coding | CA4 | No | No | 762 | P22748 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CA4 |
|---|---|
| DrugBank ID | DB00436 |
| Drug Name | Bendroflumethiazide |
| Target ID | BE0000535 |
| UniProt ID | P22748 |
| Regulation Type | inhibitor |
| PubMed IDs | 16368240; 10090333 |
| Citations | Tricarico D, Mele A, Conte Camerino D: Carbonic anhydrase inhibitors ameliorate the symptoms of hypokalaemic periodic paralysis in rats by opening the muscular Ca2+-activated-K+ channels. Neuromuscul Disord. 2006 Jan;16(1):39-45. doi: 10.1016/j.nmd.2005.10.005. Epub 2005 Dec 20.@@Wistrand PJ, Carter ND, Conroy CW, Mahieu I: Carbonic anhydrase IV activity is localized on the exterior surface of human erythrocytes. Acta Physiol Scand. 1999 Feb;165(2):211-8. doi: 10.1046/j.1365-201x.1999.00478.x. |
| Groups | Approved |
| Direct Classification | 1,2,4-benzothiadiazine-1,1-dioxides |
| SMILES | NS(=O)(=O)C1=CC2=C(NC(CC3=CC=CC=C3)NS2(=O)=O)C=C1C(F)(F)F |
| Pathways | Bendroflumethiazide Action Pathway |
| PharmGKB | PA448563 |
| ChEMBL | CHEMBL1684 |
