| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10033916 | HBV | ENSG00000137869.16 | protein_coding | CYP19A1 | Yes | No | 1588 | P11511 Q05CU4 Q8IYG4 |
| TVIS30013901 | HIV | ENSG00000137869.16 | protein_coding | CYP19A1 | Yes | No | 1588 | P11511 Q05CU4 Q8IYG4 |
| TVIS30038294 | HIV | ENSG00000137869.16 | protein_coding | CYP19A1 | Yes | No | 1588 | P11511 Q05CU4 Q8IYG4 |
| TVIS20042103 | HPV | ENSG00000137869.16 | protein_coding | CYP19A1 | Yes | No | 1588 | P11511 Q05CU4 Q8IYG4 |
| TVIS20066497 | HPV | ENSG00000137869.16 | protein_coding | CYP19A1 | Yes | No | 1588 | P11511 Q05CU4 Q8IYG4 |
| TVIS20052205 | HPV | ENSG00000137869.16 | protein_coding | CYP19A1 | Yes | No | 1588 | P11511 Q05CU4 Q8IYG4 |
| TVIS44008818 | HTLV-1 | ENSG00000137869.16 | protein_coding | CYP19A1 | Yes | No | 1588 | P11511 Q05CU4 Q8IYG4 |
| TVIS44041779 | HTLV-1 | ENSG00000137869.16 | protein_coding | CYP19A1 | Yes | No | 1588 | P11511 Q05CU4 Q8IYG4 |
| TVIS44036552 | HTLV-1 | ENSG00000137869.16 | protein_coding | CYP19A1 | Yes | No | 1588 | P11511 Q05CU4 Q8IYG4 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CYP19A1 |
|---|---|
| DrugBank ID | DB00894 |
| Drug Name | Testolactone |
| Target ID | BE0002090 |
| UniProt ID | P11511 |
| Regulation Type | inhibitor |
| PubMed IDs | 11752352; 11792932; 9521275; 16766117; 16190763 |
| Citations | Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Raman JD, Schlegel PN: Aromatase inhibitors for male infertility. J Urol. 2002 Feb;167(2 Pt 1):624-9.@@Herzog AG, Klein P, Jacobs AR: Testosterone versus testosterone and testolactone in treating reproductive and sexual dysfunction in men with epilepsy and hypogonadism. Neurology. 1998 Mar;50(3):782-4.@@Dunkel L: Use of aromatase inhibitors to increase final height. Mol Cell Endocrinol. 2006 Jul 25;254-255:207-16.@@Cepa MM, Tavares da Silva EJ, Correia-da-Silva G, Roleira FM, Teixeira NA: Structure-activity relationships of new A,D-ring modified steroids as aromatase inhibitors: design, synthesis, and biological activity evaluation. J Med Chem. 2005 Oct 6;48(20):6379-85. |
| Groups | Approved; Investigational |
| Direct Classification | Naphthopyrans |
| SMILES | [H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])CC[C@]1(C)OC(=O)CC[C@@]21[H] |
| Pathways | |
| PharmGKB | PA164743056 |
| ChEMBL | CHEMBL1571 |
