| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10033916 | HBV | ENSG00000137869.16 | protein_coding | CYP19A1 | Yes | No | 1588 | P11511 Q05CU4 Q8IYG4 |
| TVIS30013901 | HIV | ENSG00000137869.16 | protein_coding | CYP19A1 | Yes | No | 1588 | P11511 Q05CU4 Q8IYG4 |
| TVIS30038294 | HIV | ENSG00000137869.16 | protein_coding | CYP19A1 | Yes | No | 1588 | P11511 Q05CU4 Q8IYG4 |
| TVIS20042103 | HPV | ENSG00000137869.16 | protein_coding | CYP19A1 | Yes | No | 1588 | P11511 Q05CU4 Q8IYG4 |
| TVIS20066497 | HPV | ENSG00000137869.16 | protein_coding | CYP19A1 | Yes | No | 1588 | P11511 Q05CU4 Q8IYG4 |
| TVIS20052205 | HPV | ENSG00000137869.16 | protein_coding | CYP19A1 | Yes | No | 1588 | P11511 Q05CU4 Q8IYG4 |
| TVIS44008818 | HTLV-1 | ENSG00000137869.16 | protein_coding | CYP19A1 | Yes | No | 1588 | P11511 Q05CU4 Q8IYG4 |
| TVIS44041779 | HTLV-1 | ENSG00000137869.16 | protein_coding | CYP19A1 | Yes | No | 1588 | P11511 Q05CU4 Q8IYG4 |
| TVIS44036552 | HTLV-1 | ENSG00000137869.16 | protein_coding | CYP19A1 | Yes | No | 1588 | P11511 Q05CU4 Q8IYG4 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CYP19A1 |
|---|---|
| DrugBank ID | DB01006 |
| Drug Name | Letrozole |
| Target ID | BE0002090 |
| UniProt ID | P11511 |
| Regulation Type | antagonist |
| PubMed IDs | 11752352; 14505258; 15026471; 10388095 |
| Citations | Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Ebert AD, Bartley J, David M, Schweppe KW: [Aromatase inhibitors--theoretical concept and present experiences in the treatment of endometriosis]. Zentralbl Gynakol. 2003 Jul-Aug;125(7-8):247-51.@@Long BJ, Jelovac D, Handratta V, Thiantanawat A, MacPherson N, Ragaz J, Goloubeva OG, Brodie AM: Therapeutic strategies using the aromatase inhibitor letrozole and tamoxifen in a breast cancer model. J Natl Cancer Inst. 2004 Mar 17;96(6):456-65.@@Murphy MJ Jr: Molecular Action and Clinical Relevance of Aromatase Inhibitors. Oncologist. 1998;3(2):129-130. |
| Groups | Approved; Investigational |
| Direct Classification | Diphenylmethanes |
| SMILES | N#CC1=CC=C(C=C1)C(N1C=NC=N1)C1=CC=C(C=C1)C#N |
| Pathways | |
| PharmGKB | PA450196 |
| ChEMBL | CHEMBL1444 |
