| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10033916 | HBV | ENSG00000137869.16 | protein_coding | CYP19A1 | Yes | No | 1588 | P11511 Q05CU4 Q8IYG4 |
| TVIS30013901 | HIV | ENSG00000137869.16 | protein_coding | CYP19A1 | Yes | No | 1588 | P11511 Q05CU4 Q8IYG4 |
| TVIS30038294 | HIV | ENSG00000137869.16 | protein_coding | CYP19A1 | Yes | No | 1588 | P11511 Q05CU4 Q8IYG4 |
| TVIS20042103 | HPV | ENSG00000137869.16 | protein_coding | CYP19A1 | Yes | No | 1588 | P11511 Q05CU4 Q8IYG4 |
| TVIS20066497 | HPV | ENSG00000137869.16 | protein_coding | CYP19A1 | Yes | No | 1588 | P11511 Q05CU4 Q8IYG4 |
| TVIS20052205 | HPV | ENSG00000137869.16 | protein_coding | CYP19A1 | Yes | No | 1588 | P11511 Q05CU4 Q8IYG4 |
| TVIS44008818 | HTLV-1 | ENSG00000137869.16 | protein_coding | CYP19A1 | Yes | No | 1588 | P11511 Q05CU4 Q8IYG4 |
| TVIS44041779 | HTLV-1 | ENSG00000137869.16 | protein_coding | CYP19A1 | Yes | No | 1588 | P11511 Q05CU4 Q8IYG4 |
| TVIS44036552 | HTLV-1 | ENSG00000137869.16 | protein_coding | CYP19A1 | Yes | No | 1588 | P11511 Q05CU4 Q8IYG4 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CYP19A1 |
|---|---|
| DrugBank ID | DB01217 |
| Drug Name | Anastrozole |
| Target ID | BE0002090 |
| UniProt ID | P11511 |
| Regulation Type | inhibitor |
| PubMed IDs | 12404296; 14513432; 20923259 |
| Citations | Buzdar AU, Robertson JF, Eiermann W, Nabholtz JM: An overview of the pharmacology and pharmacokinetics of the newer generation aromatase inhibitors anastrozole, letrozole, and exemestane. Cancer. 2002 Nov 1;95(9):2006-16. doi: 10.1002/cncr.10908.@@Miller WR: Aromatase inhibitors: mechanism of action and role in the treatment of breast cancer. Semin Oncol. 2003 Aug;30(4 Suppl 14):3-11.@@Kelly CM, Buzdar AU: Anastrozole. Expert Opin Drug Saf. 2010 Nov;9(6):995-1003. doi: 10.1517/14740338.2010.515977. |
| Groups | Approved; Investigational |
| Direct Classification | Phenylpropanes |
| SMILES | CC(C)(C#N)C1=CC(=CC(CN2C=NC=N2)=C1)C(C)(C)C#N |
| Pathways | |
| PharmGKB | PA448432 |
| ChEMBL | CHEMBL1399 |
