Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10002892HBVENSG00000179097.7protein_codingHTR1FNoNo3355P30939
TVIS10022331HBVENSG00000179097.7protein_codingHTR1FNoNo3355P30939
TVIS10029333HBVENSG00000179097.7protein_codingHTR1FNoNo3355P30939
TVIS10045058HBVENSG00000179097.7protein_codingHTR1FNoNo3355P30939
TVIS20005969HPVENSG00000179097.7protein_codingHTR1FNoNo3355P30939
TVIS20008720HPVENSG00000179097.7protein_codingHTR1FNoNo3355P30939
TVIS20041792HPVENSG00000179097.7protein_codingHTR1FNoNo3355P30939
TVIS20022109HPVENSG00000179097.7protein_codingHTR1FNoNo3355P30939
TVIS20022108HPVENSG00000179097.7protein_codingHTR1FNoNo3355P30939
TVIS20056982HPVENSG00000179097.7protein_codingHTR1FNoNo3355P30939
TCGA Plot Options
Drug Information
GeneHTR1F
DrugBank IDDB00320
Drug NameDihydroergotamine
Target IDBE0000460
UniProt IDP30939
Regulation Typeagonist
PubMed IDs23815106; 22444161
CitationsRamirez Rosas MB, Labruijere S, Villalon CM, Maassen Vandenbrink A: Activation of 5-hydroxytryptamine1B/1D/1F receptors as a mechanism of action of antimigraine drugs. Expert Opin Pharmacother. 2013 Aug;14(12):1599-610. doi: 10.1517/14656566.2013.806487. Epub 2013 Jul 2.@@Dahlof C, Maassen Van Den Brink A: Dihydroergotamine, ergotamine, methysergide and sumatriptan - basic science in relation to migraine treatment. Headache. 2012 Apr;52(4):707-14. doi: 10.1111/j.1526-4610.2012.02124.x. Epub 2012 Mar 22.
GroupsApproved; Investigational
Direct ClassificationErgotamines, dihydroergotamines, and derivatives
SMILES[H][C@@]12CCCN1C(=O)[C@H](CC1=CC=CC=C1)N1C(=O)[C@](C)(NC(=O)[C@H]3CN(C)[C@]4([H])CC5=CNC6=CC=CC(=C56)[C@@]4([H])C3)O[C@@]21O
Pathways
PharmGKBPA164743028
ChEMBLCHEMBL1732