| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30088483 | HIV | ENSG00000164270.19 | protein_coding | HTR4 | No | No | 3360 | A0A2D3FAF9 Q13639 |
| TVIS30063793 | HIV | ENSG00000164270.19 | protein_coding | HTR4 | No | No | 3360 | A0A2D3FAF9 Q13639 |
| TVIS30063794 | HIV | ENSG00000164270.19 | protein_coding | HTR4 | No | No | 3360 | A0A2D3FAF9 Q13639 |
| TVIS20008491 | HPV | ENSG00000164270.19 | protein_coding | HTR4 | No | No | 3360 | A0A2D3FAF9 Q13639 |
| TVIS20043606 | HPV | ENSG00000164270.19 | protein_coding | HTR4 | No | No | 3360 | A0A2D3FAF9 Q13639 |
| TVIS20023643 | HPV | ENSG00000164270.19 | protein_coding | HTR4 | No | No | 3360 | A0A2D3FAF9 Q13639 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HTR4 |
|---|---|
| DrugBank ID | DB01079 |
| Drug Name | Tegaserod |
| Target ID | BE0000084 |
| UniProt ID | Q13639 |
| Regulation Type | antagonist |
| PubMed IDs | 11207504; 11876686; 12150698; 15466450; 15645012; 11752352 |
| Citations | Camilleri M: Review article: tegaserod. Aliment Pharmacol Ther. 2001 Mar;15(3):277-89.@@Kamm MA: Review article: the complexity of drug development for irritable bowel syndrome. Aliment Pharmacol Ther. 2002 Mar;16(3):343-51.@@Corsetti M, Tack J: Tegaserod: a new 5-HT(4) agonist in the treatment of irritable bowel syndrome. Expert Opin Pharmacother. 2002 Aug;3(8):1211-8.@@Beattie DT, Smith JA, Marquess D, Vickery RG, Armstrong SR, Pulido-Rios T, McCullough JL, Sandlund C, Richardson C, Mai N, Humphrey PP: The 5-HT4 receptor agonist, tegaserod, is a potent 5-HT2B receptor antagonist in vitro and in vivo. Br J Pharmacol. 2004 Nov;143(5):549-60. Epub 2004 Oct 4.@@Cole P, Rabasseda X: Tegaserod: a serotonin 5-HT4 receptor agonist for treatment of constipation-predominant irritable bowel syndrome. Drugs Today (Barc). 2004 Dec;40(12):1013-30.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved; Investigational; Withdrawn |
| Direct Classification | Indoles |
| SMILES | CCCCCNC(=N)NN=CC1=CNC2=C1C=C(OC)C=C2 |
| Pathways | |
| PharmGKB | PA130413154 |
| ChEMBL | CHEMBL76370 |
